A full list of our publications can also be found in Google Scholar, ResearcherID and ORCID.

PDF files of these publications are available upon email request.  

On the evolution of introns

  1. Ma MY, Che XR, Porceddu A and Niu DK (2015). Evaluation of the mechanisms of intron loss and gain in the social amoebae Dictyostelium. BMC Evolutionary Biology 15: 286 http://dx.doi.org/10.1186/s12862-015-0567-y.

  2. Ma MY, Zhu T, Li XN, Lan XR, Liu HY, Yang YF and Niu DK (2015). Imprecise intron losses are less frequent than precise intron losses but are not rare in plants. Biology Direct 10: 24. http://dx.doi.org/10.1186/s13062-015-0056-7.

  3. Jiang L, Li XN and Niu DK (2014). Higher frequency of intron loss from the promoter proximally paused genes of Drosophila melanogaster: Evidence consistent with delays in intron splicing as a selective force. Fly 8: 120-125. http://dx.doi.org/10.4161/fly.29489.

  4. Yang YF, Zhu T and Niu DK (2013). Association of intron loss with high mutation rate in Arabidopsis: Implications for genome size evolution. Genome Biology and Evolution 5: 723-733. doi:10.1093/gbe/evt043. This article is recommended by F1000 Victor Norris and John Herrick 2013 .

  5. Zhu T and Niu DK (2013). Mechanisms of intron loss and gain in the fission yeast Schizosaccharomyces. PLoS ONE doi:10.1371/journal.pone.0061683.

  6. Zhu T and Niu DK (2013). Frequency of intron loss correlates with processed pseudogene abundance: a novel strategy to test the reverse transcriptase model of intron loss. BMC Biology 11: 23. [Abstract/Free Full Text]

  7. Niu DK and Jiang L (2013). Can ENCODE tell us how much junk DNA we carry in our genome? Biochemical and Biophysical Research Communications 430: 1340-1343. doi:10.1016/j.bbrc.2012.12.074.

  8. Niu DK and Yang YF (2011). Why eukaryotic cells use introns to enhance gene expression: Splicing reduces transcription-associated mutagenesis by inhibiting topoisomerase I cutting activity. Biology Direct 6: 24 doi:10.1186/1745-6150-6-24 [Abstract/Free Full Text]

  9. Zhang LY, Yang YF and Niu DK (2010). Evaluation of models of the mechanisms underlying intron loss and gain in Aspergillus fungi. Journal of Molecular Evolution 71: 364-373. [Abstract]

  10. Niu DK (2008). Exon definition as a potential negative force against intron losses in evolution. Biology Direct 3: 46 doi:10.1186/1745-6150-3-46. [Abstract/Free Full Text]

  11. Huang YF and Niu DK (2008). Evidence against the energetic cost hypothesis for the short introns in highly expressed genes. BMC Evolutionary Biology 8: 154. [Abstract/Free Full Text]

  12.  Li SW, Feng L andNiu DK (2007). Selection for the miniaturization of highly expressed genes. Biochemical and Biophysical Research Communications 360: 586-592. [Abstract]

  13. Niu DK (2007). Protecting exons from deleterious R-loops: a potential advantage of having introns. Biology Direct 2: 11. [Medline] [Abstract/Free Full Text]

  14. Wang HF, Feng L and Niu DK (2007). Relationship between mRNA stability and intron presence. Biochemical and Biophysical Research Communications 354: 203-208.[Medline]

  15. Niu DK, Hou WR and Li SW (2005). mRNA-mediated intron losses: Evidence from extraordinarily large exons. Molecular Biology and Evolution 22: 1475-1481. [Abstract/Free Full Text]

On other subjects

  1. Hou WR, Li M and Niu DK (2011). Counting citations in texts rather than reference lists to improve the accuracy of assessing scientific contribution. BioEssays 33: 724-727. [Abstract] This paper has been highlighted by BioEssays: Making a deeper impact: How to measure your actual scientific footprint?  

  2. Niu DK and Cao JL (2010). Nucleosome deposition and DNA methylation may participate in the recognition of premature termination codon in nonsense-mediated mRNA decay. FEBS Letters 584: 3509-3512. 

  3. Li N, Lv J and Niu DK (2009). Low contents of carbon and nitrogen in highly abundant proteins: Evidence of selection for the economy of atomic composition. Journal of Molecular Evolution 68: 248-255. 

  4. Lv J, Li N and Niu DK (2008). Association between the availability of environmental resources and the atomic composition of organismal proteomes: Evidence from Prochlorococcus strains living at different depths. Biochemical and Biophysical Research Communications 375: 241-246. 

  5. Wang HF, Hou WR and Niu DK (2008). Strand compositional asymmetries in vertebrate large genes. Molecular Biology Reports  35: 163-169. 

  6. Feng L and Niu DK (2007). Relationship between mRNA stability and length: An old question with a new twist, Biochemical Genetics 45: 131-137.

  7. Hou WR, Wang HF and Niu DK (2006). Replication-associated strand asymmetries in vertebrate genomes and implications for replicon size, DNA replication origin and termination. Biochemical and Biophysical Research Communications 344: 1258-1262. 

  8. Niu DK (2005). Low-level illegitimate transcription of genes may be to silence the genes. Biochemical and Biophysical Research Communications 337:413-414. 

  9. Song L, Niu DK, Lei L, Ou D, Gevrey M, Liu Y, Hou G and Lek S (2004). Predictive model of algal blooms in Dianchi Lake using artificial neural networks. The Japanese Journal of Phycology 52: S41-S47.

  10. Niu DK, Lin K and Zhang DY (2003). Strand compositional asymmetries of nuclear DNA in eukaryotes. Journal of Molecular Evolution 57: 325-334. 

  11. Niu, D. K., Chen, J.-K. and Liu, Y.–D. (2001). Margulis' theory on division of labour in cells revisited. Acta Biotheoretica 49: 23-28. 

  12. Niu, D. K. and Chen, J.-K. (1998/1999). Origin of cancerous cells from tumour. Acta Biotheoretica 46: 379-381. 

  13. Niu, D. K. and Chen, J.-K. (1997). Evolutionary advantages of cell specialization: Save and protect DNA. Journal of Theoretical Biology 187: 39-43. 

  14. Niu, D. K., Wang, M. G. and Wang, Y. F. (1997). Plant cellular osmotica. Acta Biotheoretica 45: 161-169.

  15. Niu, D. K. and Wang Y. F. (1995). Why animals have tumours. Acta Biotheoretica 43: 279-280. Now, the first author does not hold such idea. He is now searching for other possible answers for “why animals have tumours”.

  16. And several papers in Chinese with English abstracts.

主持的科研项目

  1. 北京师范大学自主科研基金项目，2014KJJCB18，真核生物编码蛋白质基因内部结构进化，2014/09-2017/08，35万元

  2. 国家自然科学基金面上项目，31371283，基因组大小与内含子进化的比较研究，2014/01-2017/12，80万元

  3. 国家自然科学基金面上项目，31071112，近缘物种间和物种内内含子数目变异的进化机制，2011/01-2013/12，35万元

  4. 教育部新世纪优秀人才支持计划，2008年，生物与基础医学，50万元

  5. 国家自然科学基金面上项目，30270695，多细胞生物起源及其与癌发生的比较研究，2003/01-2005/12，18万元

参加的科研项目

  1. 国家自然科学基金创新研究群体项目，31421063，生物多样性的维持机制，2015/01-2017/12，600万元

  2. 国家自然科学基金重大研究计划《微进化过程的多基因作用机制》的培育项目，91231119，极端微生物宏基因组微进化的计算生物学研究，2013/01-2015/12，100万元

  3. 国家自然科学基金创新研究群体项目，31121003，生物多样性的维持机制，2012/01-2014/12，600万元

Make a Free Website with Yola.